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SCIENTIFIC SCORE
Possibly Effective
Based on 59 Researches
7.2
USERS' SCORE
Good
Based on 16 Reviews
8.5
Supplement Facts
Serving Size: 1 Teaspoon (5 ml)
Amount Per Serving
%DV
Calories
40
Total Fat
4.5 g
6%**
Saturated Fat
0.5 g
3%**
Cholesterol
15 mg
5%
Vitamin A (from cod liver oil and retinyl palmitate)
255 mcg RAE(850 IU)
28%
Vitamin D (from cod liver oil and cholecalciferol)
10 mcg (400 IU)
50%
Vitamin E (as d-alpha tocopherol)
6.7 mg
45%
Norwegian Cod Liver Oil
4.6 g
†
Total Omega-3 Fatty Acids*
1,100 mg
†
DHA (Docosahexaenoic Acid)*
500 mg
†
EPA (Eicosapentaenoic Acid)*
370 mg
†
DPA (Docosapentaenoic Acid)*
50 mg
†
Top Medical Research Studies
9
DHA lowers cholesterol; boosts metabolism
F-Fluorodeoxyglucose positron emission tomography/computed tomography imaging reveals the protective effect of docosahexaenoic acid on glucose metabolism by reducing brain 27-hydroxycholesterol.
Directly addresses cholesterol effects
We aimed to investigate how docosahexaenoic acid (DHA) impacts cholesterol levels and brain glucose metabolism. In our study, we focused on aged SAMP8 mice, dividing them into two groups: a control group and one receiving DHA supplementation.
Our results revealed encouraging changes; the group that received DHA showed a decrease in total cholesterol and low-density lipoprotein cholesterol, while high-density lipoprotein cholesterol levels increased. More importantly, we observed improvements in glucose metabolism in various brain regions, including the cortex and hippocampus.
These findings suggest that DHA may help lower harmful cholesterol levels and enhance brain function by regulating specific cholesterol compounds like 27-hydroxycholesterol, which are linked to glucose metabolism. Overall, our study highlights DHA's potential in supporting heart and brain health through cholesterol management.
Our results revealed encouraging changes; the group that received DHA showed a decrease in total cholesterol and low-density lipoprotein cholesterol, while high-density lipoprotein cholesterol levels increased. More importantly, we observed improvements in glucose metabolism in various brain regions, including the cortex and hippocampus.
These findings suggest that DHA may help lower harmful cholesterol levels and enhance brain function by regulating specific cholesterol compounds like 27-hydroxycholesterol, which are linked to glucose metabolism. Overall, our study highlights DHA's potential in supporting heart and brain health through cholesterol management.
Read More
9
Eicosapentaenoic acid benefits cholesterol
Omega-3 eicosapentaenoic polar-lipid rich extract from microalgae decreases plasma triglycerides and cholesterol in a real-world normolipidemic supplement consumer population.
Direct focus on EPA's efficacy
We explored the effects of eicosapentaenoic acid (EPA), a specific type of omega-3 fatty acid, on cholesterol levels in a recent study involving real-world supplement consumers. Participants took AlmegaPL capsules, which contain high amounts of EPA and are free of the other omega-3 fatty acid, DHA. This setup allowed us to gain insights from those who are already incorporating EPA into their diets.
Throughout the study, we monitored key health markers such as triglycerides, total cholesterol, and various types of cholesterol at different stages of supplementation. We observed that after six months of taking this supplement, participants showed a significant reduction in remnant cholesterol and maintained healthy triglyceride levels. Notably, this decrease in cholesterol did not come at the expense of raising low-density lipoprotein (LDL) levels, which is often a concern with other treatments.
These encouraging results reveal that EPA can be a beneficial addition for individuals looking to manage their cholesterol levels effectively. Importantly, our findings highlight AlmegaPL's unique position as a natural, over-the-counter option for those seeking to improve their lipid profiles.
Throughout the study, we monitored key health markers such as triglycerides, total cholesterol, and various types of cholesterol at different stages of supplementation. We observed that after six months of taking this supplement, participants showed a significant reduction in remnant cholesterol and maintained healthy triglyceride levels. Notably, this decrease in cholesterol did not come at the expense of raising low-density lipoprotein (LDL) levels, which is often a concern with other treatments.
These encouraging results reveal that EPA can be a beneficial addition for individuals looking to manage their cholesterol levels effectively. Importantly, our findings highlight AlmegaPL's unique position as a natural, over-the-counter option for those seeking to improve their lipid profiles.
Read More
9
DPA improves cholesterol levels
Differential effects of EPA, DPA and DHA on cardio-metabolic risk factors in high-fat diet fed mice.
Focus on DPA's cholesterol impact
We explored the effects of docosapentaenoic acid (DPA) on cholesterol levels in mice consuming a high-fat diet. This study involved male C57BL/6J mice that were observed after being fed a high-fat diet for six weeks. Notably, the mice developed symptoms like fatty liver, obesity, and insulin resistance, which became a useful model for understanding how dietary fats can impact health.
When we supplemented the high-fat diet with DPA, we found significant improvements. The DPA helped prevent the buildup of cholesterol in the liver and lower serum cholesterol and glucose levels. Interestingly, while both DPA and docosahexaenoic acid (DHA) provided similar benefits, DPA stood out for significantly enhancing insulin sensitivity—a critical factor in managing metabolic health.
Additionally, we noticed that DPA, along with DHA, helped to maintain normal serum adiponectin levels, which are important for regulating glucose and fatty acid levels in the body. The study further showed that DPA's protective effects are largely attributed to its ability to downregulate certain inflammatory pathways, which could be beneficial for overall cardiovascular health.
In summary, incorporating DPA into a high-fat diet appears to offer significant advantages in managing cholesterol levels and metabolic health, indicating that this nutrient could play a valuable role in dietary interventions for high cholesterol.
When we supplemented the high-fat diet with DPA, we found significant improvements. The DPA helped prevent the buildup of cholesterol in the liver and lower serum cholesterol and glucose levels. Interestingly, while both DPA and docosahexaenoic acid (DHA) provided similar benefits, DPA stood out for significantly enhancing insulin sensitivity—a critical factor in managing metabolic health.
Additionally, we noticed that DPA, along with DHA, helped to maintain normal serum adiponectin levels, which are important for regulating glucose and fatty acid levels in the body. The study further showed that DPA's protective effects are largely attributed to its ability to downregulate certain inflammatory pathways, which could be beneficial for overall cardiovascular health.
In summary, incorporating DPA into a high-fat diet appears to offer significant advantages in managing cholesterol levels and metabolic health, indicating that this nutrient could play a valuable role in dietary interventions for high cholesterol.
Read More
Most Useful Reviews
9.5
Best brand choice
Excellent quality! Among healthy fats, I prefer Carlson. When choosing omega-3, focus on DHA concentration, as it’s vital for the body. Ensure high EPA and DHA levels in the formula for optimal benefits in managing high cholesterol.
Read More
9.5
Improves cholesterol levels
Carlson has been a fantastic find for both heart and skin health. The fat from wild Norwegian cod is a true source of omega-3 that’s easy to use and tastes pleasant. After regular use, I've noticed improvements in my energy and overall well-being.
Read More
9.5
Effective ingredients
Good quality fish oil with excellent ingredients, including Omega, vitamins A and E. It noticeably assists in managing high cholesterol. The citrus flavour is nice, but the natural taste has a slight fishiness. Despite the high price, it's worth it. I recommend it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 59 Researches
7.2
9
Cod liver oil aids cholesterol reduction
Role of Cod Liver Oil in Reducing Elevated Lipid Parameters.
Study supports combined therapy
We conducted an insightful study to examine the effects of cod liver oil on high cholesterol levels. The research was carried out in a well-structured manner, with 600 participants who had elevated cholesterol and low-density lipoprotein (LDL) levels. These individuals were divided into two groups. One group received daily doses of 415 mg of cod liver oil along with 10 mg of rosuvastatin, while the other group received just the rosuvastatin with placebo capsules.
After 30 days, we observed compelling results. The group taking cod liver oil showed a more significant drop in total cholesterol levels compared to those who only took rosuvastatin. Specifically, their total cholesterol fell to 152.22 mg/dL compared to 171.65 mg/dL in the control group. Similarly, LDL levels decreased more in the cod liver oil group, highlighting its potential benefits when added to standard cholesterol treatment.
However, it's crucial to mention that while cod liver oil seems to enhance the effect of rosuvastatin, lifestyle changes should still be the primary focus for anyone managing high cholesterol. This study opens the door for further research to explore the specific benefits of cod liver oil in such treatments.
After 30 days, we observed compelling results. The group taking cod liver oil showed a more significant drop in total cholesterol levels compared to those who only took rosuvastatin. Specifically, their total cholesterol fell to 152.22 mg/dL compared to 171.65 mg/dL in the control group. Similarly, LDL levels decreased more in the cod liver oil group, highlighting its potential benefits when added to standard cholesterol treatment.
However, it's crucial to mention that while cod liver oil seems to enhance the effect of rosuvastatin, lifestyle changes should still be the primary focus for anyone managing high cholesterol. This study opens the door for further research to explore the specific benefits of cod liver oil in such treatments.
Read More
9
Krill oil supports cholesterol management
Antarctic Krill Oil Supplementation Attenuates Hypercholesterolemia, Fatty Liver, and Oxidative Stress in Diet-Induced Obese Mice.
Moderate relevance for DHA impact
We explored how Antarctic krill oil, particularly its key components like docosahexaenoic acid (DHA), can combat high cholesterol and obesity-related issues. Our study focused on its effects in a controlled environment using obese mice that were fed a high-fat diet.
We observed that when these mice were supplemented with krill oil, there were notable reductions in cholesterol levels and fat accumulation. It seemed to positively influence various metabolic pathways, such as those associated with cholesterol metabolism.
Specifically, DHA, along with other nutrients found in krill oil, appears to aid in lowering oxidative stress and improving cholesterol metabolism. While the benefits of DHA alone weren't isolated in this study, the overall findings suggest that krill oil may work effectively in reducing the risks tied to obesity and high cholesterol.
Overall, this research indicates that incorporating krill oil into our diets could be a promising strategy for managing cholesterol levels and supporting heart health.
We observed that when these mice were supplemented with krill oil, there were notable reductions in cholesterol levels and fat accumulation. It seemed to positively influence various metabolic pathways, such as those associated with cholesterol metabolism.
Specifically, DHA, along with other nutrients found in krill oil, appears to aid in lowering oxidative stress and improving cholesterol metabolism. While the benefits of DHA alone weren't isolated in this study, the overall findings suggest that krill oil may work effectively in reducing the risks tied to obesity and high cholesterol.
Overall, this research indicates that incorporating krill oil into our diets could be a promising strategy for managing cholesterol levels and supporting heart health.
Read More
9
DHA supplementation for cholesterol management
EPA and DHA inhibit LDL-induced upregulation of human adipose tissue NLRP3 inflammasome/IL-1β pathway and its association with diabetes risk factors.
Study highlights DHA's impact
We explored how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, influences levels of bad cholesterol and related diabetes risk. In a comprehensive study, participants were given a daily supplement of both EPA and DHA for twelve weeks. This supplementation aimed to see if it could counteract the negative effects of low-density lipoproteins (LDL) on human adipose tissue.
The results were quite revealing. Before the intervention, we noticed a significant difference in interleukin-1 beta (IL-1β) secretion, a pro-inflammatory substance linked to higher cholesterol levels, between individuals with high and low levels of atherogenic lipoproteins (apoB). After the supplementation with EPA and DHA, this inflammatory response was significantly reduced in those with high apoB. Not only did the fatty acids inhibit IL-1β secretion triggered by LDL, but they also improved fat metabolism and insulin response.
Furthermore, we observed that the omega-3 supplementation addressed various cardiometabolic risk factors, including those related to adiposity. The study indicated that DHA, alongside EPA, plays a role in managing inflammatory responses that contribute to high cholesterol levels and diabetes risk.
In conclusion, incorporating DHA as part of omega-3 supplementation could be a valuable strategy for those with elevated cholesterol levels, especially in preventing type 2 diabetes and its associated health issues.
The results were quite revealing. Before the intervention, we noticed a significant difference in interleukin-1 beta (IL-1β) secretion, a pro-inflammatory substance linked to higher cholesterol levels, between individuals with high and low levels of atherogenic lipoproteins (apoB). After the supplementation with EPA and DHA, this inflammatory response was significantly reduced in those with high apoB. Not only did the fatty acids inhibit IL-1β secretion triggered by LDL, but they also improved fat metabolism and insulin response.
Furthermore, we observed that the omega-3 supplementation addressed various cardiometabolic risk factors, including those related to adiposity. The study indicated that DHA, alongside EPA, plays a role in managing inflammatory responses that contribute to high cholesterol levels and diabetes risk.
In conclusion, incorporating DHA as part of omega-3 supplementation could be a valuable strategy for those with elevated cholesterol levels, especially in preventing type 2 diabetes and its associated health issues.
Read More
9
DHA lowers cholesterol; boosts metabolism
F-Fluorodeoxyglucose positron emission tomography/computed tomography imaging reveals the protective effect of docosahexaenoic acid on glucose metabolism by reducing brain 27-hydroxycholesterol.
Directly addresses cholesterol effects
We aimed to investigate how docosahexaenoic acid (DHA) impacts cholesterol levels and brain glucose metabolism. In our study, we focused on aged SAMP8 mice, dividing them into two groups: a control group and one receiving DHA supplementation.
Our results revealed encouraging changes; the group that received DHA showed a decrease in total cholesterol and low-density lipoprotein cholesterol, while high-density lipoprotein cholesterol levels increased. More importantly, we observed improvements in glucose metabolism in various brain regions, including the cortex and hippocampus.
These findings suggest that DHA may help lower harmful cholesterol levels and enhance brain function by regulating specific cholesterol compounds like 27-hydroxycholesterol, which are linked to glucose metabolism. Overall, our study highlights DHA's potential in supporting heart and brain health through cholesterol management.
Our results revealed encouraging changes; the group that received DHA showed a decrease in total cholesterol and low-density lipoprotein cholesterol, while high-density lipoprotein cholesterol levels increased. More importantly, we observed improvements in glucose metabolism in various brain regions, including the cortex and hippocampus.
These findings suggest that DHA may help lower harmful cholesterol levels and enhance brain function by regulating specific cholesterol compounds like 27-hydroxycholesterol, which are linked to glucose metabolism. Overall, our study highlights DHA's potential in supporting heart and brain health through cholesterol management.
Read More
9
Eicosapentaenoic acid aids cholesterol
Antarctic Krill Oil Supplementation Attenuates Hypercholesterolemia, Fatty Liver, and Oxidative Stress in Diet-Induced Obese Mice.
Study shows EPA's combined effects
We explored the effects of eicosapentaenoic acid (EPA) from Antarctic krill oil (ESKO) on cholesterol levels and obesity-related conditions. Through a carefully designed study involving mice on a high-fat diet, we wanted to see if ESKO could improve cholesterol metabolism and reduce fat accumulation.
We found that diets high in fat significantly increased oxidative stress and indicators associated with obesity. However, supplementation with ESKO appeared to counteract these negative effects, helping to reduce fat buildup and improve cholesterol levels.
Specifically, ESKO improved important metabolic pathways and reduced the activity of certain proteins that typically promote high cholesterol. This suggests that eicosapentaenoic acid from krill oil could play a crucial role in tackling high cholesterol and obesity-related disorders.
We found that diets high in fat significantly increased oxidative stress and indicators associated with obesity. However, supplementation with ESKO appeared to counteract these negative effects, helping to reduce fat buildup and improve cholesterol levels.
Specifically, ESKO improved important metabolic pathways and reduced the activity of certain proteins that typically promote high cholesterol. This suggests that eicosapentaenoic acid from krill oil could play a crucial role in tackling high cholesterol and obesity-related disorders.
Read More
User Reviews
USERS' SCORE
Good
Based on 16 Reviews
8.5
9.5
Best brand choice
Excellent quality! Among healthy fats, I prefer Carlson. When choosing omega-3, focus on DHA concentration, as it’s vital for the body. Ensure high EPA and DHA levels in the formula for optimal benefits in managing high cholesterol.
9.5
Improves cholesterol levels
Carlson has been a fantastic find for both heart and skin health. The fat from wild Norwegian cod is a true source of omega-3 that’s easy to use and tastes pleasant. After regular use, I've noticed improvements in my energy and overall well-being.
9.5
Effective ingredients
Good quality fish oil with excellent ingredients, including Omega, vitamins A and E. It noticeably assists in managing high cholesterol. The citrus flavour is nice, but the natural taste has a slight fishiness. Despite the high price, it's worth it. I recommend it.
9.5
Immunity booster
Natural purified fish oil from cod liver boosts immunity, hydrates skin, and supports the cardiovascular system. It has a high omega-3 concentration and a neutral taste. I recommend it for treating high cholesterol.
9.5
Improved health
The pleasant taste of this omega-3 surprised me. It’s great for heart health and proper body functioning, aiding good cholesterol levels and reducing inflammation. I'm using it for my son as well.
